Measurement of TPO Ab and TG Ab levels and its association with thyroid dysfunction in Graves’ disease patients in Najaf city

Graves’ disease (GD) is a common autoimmune that accounts for the majority of cases hyperthyroidism in developed world (Rich & Fleisher, 2018) Autoimmune thyroid Graves' one most (AID), affecting 13 million people and targeting women seven times as often men. It affects young to middle-aged adults but can occur at all ages.(Vos et al., 2009). Aim The study determination TPO Ab levels TG its correlation with dysfunction patients. A Case - control was done on 100 patients GD diagnosed three hospitals Najaf city Iraq, Al-Sadr Teaching Hospital, Al-Hakim General Al-Najaf Hospitals, respectively, group 32 healthy individual control. Blood sample collected from were measured by enzyme-linked immunosorbent assay (ELISA). While TSH, T3 T4 hormones Cobas e 411 analyzer. result shown female (89%) more than male (11%), mean age (36.86) highest other age. This explain there high significant T4. Also patient compared group.